Northwestern University Feinberg School of Medicine

Program in Endocrinology, Diabetes and Hormone Action

Publications

Below is a list of publications associated with NUPEDHA.
  1. Dapas M, Lin FTJ, Nadkarni GN, Sisk R, Legro RS, Urbanek M, Hayes MG, Dunaif A  Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.  PLoS Med  2020 06;17(6):e1003132. doi:10.1371/journal.pmed.1003132
  2. Dapas M, Dunaif A  The contribution of rare genetic variants to the pathogenesis of polycystic ovary syndrome.  Curr Opin Endocr Metab Res  2020 Jun;12:26-32. doi:10.1016/j.coemr.2020.02.011
  3. Soundarrajan M, Deng J, Kwasny M, Rubert NC, Nelson PC, El-Seoud DA, Landsberg L, Neff LM  Activated brown adipose tissue and its relationship to adiposity and metabolic markers: an exploratory study.  Adipocyte  2020 12;9(1):87-95. doi:10.1080/21623945.2020.1724740
  4. Pottinger TD, Puckelwartz MJ, Pesce LL, Robinson A, Kearns S, Pacheco JA, Rasmussen-Torvik LJ, Smith ME, Chisholm R, McNally EM  Pathogenic and Uncertain Genetic Variants Have Clinical Cardiac Correlates in Diverse Biobank Participants.  J Am Heart Assoc  2020 Feb 04;9(3):e013808. doi:10.1161/JAHA.119.013808
  5. Soundarrajan M, Zelada H, Fischer JV, Kopp P  ECTOPIC ADRENOCORTICOTROPIC HORMONE SYNDROME DUE TO METASTATIC PROSTATE CANCER WITH NEUROENDOCRINE DIFFERENTIATION.  AACE Clin Case Rep  ;5(3):e192-e196. doi:10.4158/ACCR-2018-0429
  6. Masters MC, Krueger KM, Williams JL, Morrison L, Cohn SE  Beyond one pill, once daily: current challenges of antiretroviral therapy management in the United States.  Expert Rev Clin Pharmacol  2019 Dec;12(12):1129-1143. doi:10.1080/17512433.2019.1698946
  7. Taylor MJ, Ullenbruch MR, Frucci EC, Rege J, Ansorge MS, Gomez-Sanchez CE, Begum S, Laufer E, Breault DT, Rainey WE  Chemogenetic activation of adrenocortical Gq signaling causes hyperaldosteronism and disrupts functional zonation.  J Clin Invest  2020 01 02;130(1):83-93. doi:10.1172/JCI127429
  8. Masters MC, Perez J, Tassiopoulos K, Andrade A, Ellis R, Yang J, Brown TT, Palella FJ, Erlandson KM  Gait Speed Decline Is Associated with Hemoglobin A1C, Neurocognitive Impairment, and Black Race in Persons with HIV.  AIDS Res Hum Retroviruses  ;35(11-12):1065-1073. doi:10.1089/AID.2019.0101
  9. Robertson K, Landay A, Miyahara S, Vecchio A, Masters MC, Brown TT, Taiwo BO  Limited correlation between systemic biomarkers and neurocognitive performance before and during HIV treatment.  J Neurovirol  2020 02;26(1):107-113. doi:10.1007/s13365-019-00795-2
  10. Kelly SG, Masters MC, Taiwo BO  Initial Antiretroviral Therapy in an Integrase Inhibitor Era: Can We Do Better?  Infect Dis Clin North Am  2019 09;33(3):681-692. pii:S0891-5520(19)30039-X
  11. Garcia-Moreno SA, Lin YT, Futtner CR, Salamone IM, Capel B, Maatouk DM  CBX2 is required to stabilize the testis pathway by repressing Wnt signaling.  PLoS Genet  2019 05;15(5):e1007895. doi:10.1371/journal.pgen.1007895
  12. Dapas M, Sisk R, Legro RS, Urbanek M, Dunaif A, Hayes MG  Family-based quantitative trait meta-analysis implicates rare noncoding variants in DENND1A in polycystic ovary syndrome.  J Clin Endocrinol Metab  2019 Apr 30;. pii:jc.2018-02496
  13. Levine JA, Karam SL, O'Connor C, Kumar S, Soundarrajan M, McConnell D, Ammar AT, Gale AM, Zimmerman D, Szmuilowicz ED  CENTRAL DIABETES INSIPIDUS AND CHEMOTHERAPY: USE OF A CONTINUOUS ARGININE VASOPRESSIN INFUSION FOR FLUID AND SODIUM BALANCE.  AACE Clin Case Rep  ;4(6):e487-e492. doi:10.4158/ACCR-2018-0165
  14. Zelikovich AS, Quattrocelli M, Salamone IM, Kuntz NL, McNally EM  Moderate exercise improves function and increases adiponectin in the mdx mouse model of muscular dystrophy.  Sci Rep  2019 04 08;9(1):5770. doi:10.1038/s41598-019-42203-z
  15. Li S, Fong KW, Gritsina G, Zhang A, Zhao JC, Kim J, Sharp A, Yuan W, Aversa C, Yang XJ, Nelson PS, Feng FY, Chinnaiyan AM, de Bono JS, Morrissey C, Rettig MB, Yu J  Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer.  Cancer Res  2019 05 15;79(10):2580-2592. doi:10.1158/0008-5472.CAN-18-2812
  16. Garcia-Moreno SA, Futtner CR, Salamone IM, Gonen N, Lovell-Badge R, Maatouk DM  Gonadal supporting cells acquire sex-specific chromatin landscapes during mammalian sex determination.  Dev Biol  2019 02 15;446(2):168-179. pii:S0012-1606(18)30497-4
  17. Kim J, Lee Y, Lu X, Song B, Fong KW, Cao Q, Licht JD, Zhao JC, Yu J  Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator.  Cell Rep  2018 12 04;25(10):2808-2820.e4. pii:S2211-1247(18)31798-4
  18. Pusec CM, De Jesus A, Khan MW, Terry AR, Ludvik AE, Xu K, Giancola N, Pervaiz H, Daviau Smith E, Ding X, Harrison S, Chandel NS, Becker TC, Hay N, Ardehali H, Cordoba-Chacon J, Layden BT  Hepatic HKDC1 Expression Contributes to Liver Metabolism.  Endocrinology  2019 02 01;160(2):313-330. doi:10.1210/en.2018-00887
  19. Chen W, Hoffmann AD, Liu H, Liu X  Organotropism: new insights into molecular mechanisms of breast cancer metastasis.  NPJ Precis Oncol  2018;2(1):4. doi:10.1038/s41698-018-0047-0
  20. Gerber C, Cai X, Lee J, Craven T, Scialla J, Souma N, Srivastava A, Mehta R, Paluch A, Hodakowski A, Frazier R, Carnethon MR, Wolf MS, Isakova T  Incidence and Progression of Chronic Kidney Disease in Black and White Individuals with Type 2 Diabetes.  Clin J Am Soc Nephrol  2018 06 07;13(6):884-892. doi:10.2215/CJN.11871017
  21. Ramos EK, Hoffmann AD, Gerson SL, Liu H  New Opportunities and Challenges to Defeat Cancer Stem Cells.  Trends Cancer  2017 11;3(11):780-796. pii:S2405-8033(17)30174-7
  22. Eren M, Place AT, Thomas PM, Flevaris P, Miyata T, Vaughan DE  PAI-1 is a critical regulator of FGF23 homeostasis.  Sci Adv  2017 09;3(9):e1603259. doi:10.1126/sciadv.1603259
  23. Villa SR, Mishra RK, Zapater JL, Priyadarshini M, Gilchrist A, Mancebo H, Schiltz GE, Layden BT  Homology modeling of FFA2 identifies novel agonists that potentiate insulin secretion.  J Investig Med  2017 12;65(8):1116-1124. doi:10.1136/jim-2017-000523
  24. Sam S, Vellanki P, Yalamanchi SK, Bergman RN, Dunaif A  Exaggerated glucagon responses to hypoglycemia in women with polycystic ovary syndrome.  Metabolism  2017 06;71:125-131. pii:S0026-0495(17)30088-4
  25. Gorsic LK, Kosova G, Werstein B, Sisk R, Legro RS, Hayes MG, Teixeira JM, Dunaif A, Urbanek M  Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome.  J Clin Endocrinol Metab  2017 08 01;102(8):2862-2872. doi:10.1210/jc.2017-00612
  26. Kim J, Jin H, Zhao JC, Yang YA, Li Y, Yang X, Dong X, Yu J  FOXA1 inhibits prostate cancer neuroendocrine differentiation.  Oncogene  2017 07 13;36(28):4072-4080. doi:10.1038/onc.2017.50
  27. Sandler V, Reisetter AC, Bain JR, Muehlbauer MJ, Nodzenski M, Stevens RD, Ilkayeva O, Lowe LP, Metzger BE, Newgard CB, Scholtens DM, Lowe WL,   Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes.  Diabetologia  2017 03;60(3):518-530. doi:10.1007/s00125-016-4182-2
  28. Fong KW, Zhao JC, Kim J, Li S, Yang YA, Song B, Rittie L, Hu M, Yang X, Perbal B, Yu J  Polycomb-Mediated Disruption of an Androgen Receptor Feedback Loop Drives Castration-Resistant Prostate Cancer.  Cancer Res  2017 01 15;77(2):412-422. doi:10.1158/0008-5472.CAN-16-1949
  29. Ludvik AE, Pusec CM, Priyadarshini M, Angueira AR, Guo C, Lo A, Hershenhouse KS, Yang GY, Ding X, Reddy TE, Lowe WL, Layden BT  HKDC1 Is a Novel Hexokinase Involved in Whole-Body Glucose Use.  Endocrinology  2016 09;157(9):3452-61. doi:10.1210/en.2016-1288
  30. Villa SR, Priyadarshini M, Fuller MH, Bhardwaj T, Brodsky MR, Angueira AR, Mosser RE, Carboneau BA, Tersey SA, Mancebo H, Gilchrist A, Mirmira RG, Gannon M, Layden BT  Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival.  Sci Rep  2016 06 21;6:28159. doi:10.1038/srep28159
  31. Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F  Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male.  Cell Metab  2016 May 10;23(5):837-51. doi:10.1016/j.cmet.2016.03.015
  32. Dapas M, Kandpal M, Bi Y, Davuluri RV  Comparative evaluation of isoform-level gene expression estimation algorithms for RNA-seq and exon-array platforms.  Brief Bioinform  2017 03 01;18(2):260-269. doi:10.1093/bib/bbw016
  33. Monsivais D, Dyson MT, Yin P, Navarro A, Coon JS, Pavone ME, Bulun SE  Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation.  Fertil Steril  2016 05;105(5):1266-1273. pii:S0015-0282(16)00047-9
  34. Perelis M, Marcheva B, Ramsey KM, Schipma MJ, Hutchison AL, Taguchi A, Peek CB, Hong H, Huang W, Omura C, Allred AL, Bradfield CA, Dinner AR, Barish GD, Bass J  Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion.  Science  2015 Nov 06;350(6261):aac4250. doi:10.1126/science.aac4250
  35. Dyson MT, Kakinuma T, Pavone ME, Monsivais D, Navarro A, Malpani SS, Ono M, Bulun SE  Aberrant expression and localization of deoxyribonucleic acid methyltransferase 3B in endometriotic stromal cells.  Fertil Steril  2015 Oct;104(4):953-963.e2. pii:S0015-0282(15)00475-6
  36. Priyadarshini M, Villa SR, Fuller M, Wicksteed B, Mackay CR, Alquier T, Poitout V, Mancebo H, Mirmira RG, Gilchrist A, Layden BT  An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.  Mol Endocrinol  2015 Jul;29(7):1055-66. doi:10.1210/me.2015-1007
  37. Yin P, Ono M, Moravek MB, Coon JS, Navarro A, Monsivais D, Dyson MT, Druschitz SA, Malpani SS, Serna VA, Qiang W, Chakravarti D, Kim JJ, Bulun SE  Human uterine leiomyoma stem/progenitor cells expressing CD34 and CD49b initiate tumors in vivo.  J Clin Endocrinol Metab  2015 Apr;100(4):E601-6. doi:10.1210/jc.2014-2134
  38. Guo C, Ludvik AE, Arlotto ME, Hayes MG, Armstrong LL, Scholtens DM, Brown CD, Newgard CB, Becker TC, Layden BT, Lowe WL, Reddy TE  Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1.  Nat Commun  2015 Feb 04;6:6069. doi:10.1038/ncomms7069
  39. Vellanki P, Umpierrez GE  Iatrogenic hypoglycemia and quality of life in patients with type 2 diabetes mellitus.  Rev Clin Esp  2015 Mar;215(2):104-6. doi:10.1016/j.rce.2014.11.017
  40. Angueira AR, Ludvik AE, Reddy TE, Wicksteed B, Lowe WL, Layden BT  New insights into gestational glucose metabolism: lessons learned from 21st century approaches.  Diabetes  2015 Feb;64(2):327-34. doi:10.2337/db14-0877
  41. Moravek MB, Yin P, Ono M, Coon JS, Dyson MT, Navarro A, Marsh EE, Chakravarti D, Kim JJ, Wei JJ, Bulun SE  Ovarian steroids, stem cells and uterine leiomyoma: therapeutic implications.  Hum Reprod Update  ;21(1):1-12. doi:10.1093/humupd/dmu048
  42. Moy I, Todorović V, Dubash AD, Coon JS, Parker JB, Buranapramest M, Huang CC, Zhao H, Green KJ, Bulun SE  Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells.  Oncogene  2015 Jan 15;34(3):323-33. doi:10.1038/onc.2013.553