Northwestern University Feinberg School of Medicine

Program in Endocrinology, Diabetes and Hormone Action


Below is a list of publications associated with NUPEDHA.
  1. Levine JA, Oleaga C, Eren M, Amaral AP, Shang M, Lux E, Khan SS, Shah SJ, Omura Y, Pamir N, Hay J, Barish G, Miyata T, Tavori H, Fazio S, Vaughan DE  Role of PAI-1 in hepatic steatosis and dyslipidemia.  Sci Rep  2021 Jan 11;11(1):430. doi:10.1038/s41598-020-79948-x
  2. Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Fox JEM, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J  A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.  Genes Dev  2020 Aug 01;34(15-16):1089-1105. doi:10.1101/gad.338178.120
  3. Dapas M, Lin FTJ, Nadkarni GN, Sisk R, Legro RS, Urbanek M, Hayes MG, Dunaif A  Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.  PLoS Med  2020 06;17(6):e1003132. doi:10.1371/journal.pmed.1003132
  4. Dapas M, Dunaif A  The contribution of rare genetic variants to the pathogenesis of polycystic ovary syndrome.  Curr Opin Endocr Metab Res  2020 Jun;12:26-32. doi:10.1016/j.coemr.2020.02.011
  5. Pottinger TD, Puckelwartz MJ, Pesce LL, Robinson A, Kearns S, Pacheco JA, Rasmussen-Torvik LJ, Smith ME, Chisholm R, McNally EM  Pathogenic and Uncertain Genetic Variants Have Clinical Cardiac Correlates in Diverse Biobank Participants.  J Am Heart Assoc  2020 02 04;9(3):e013808. doi:10.1161/JAHA.119.013808
  7. Masters MC, Krueger KM, Williams JL, Morrison L, Cohn SE  Beyond one pill, once daily: current challenges of antiretroviral therapy management in the United States.  Expert Rev Clin Pharmacol  2019 Dec;12(12):1129-1143. doi:10.1080/17512433.2019.1698946
  8. Taylor MJ, Ullenbruch MR, Frucci EC, Rege J, Ansorge MS, Gomez-Sanchez CE, Begum S, Laufer E, Breault DT, Rainey WE  Chemogenetic activation of adrenocortical Gq signaling causes hyperaldosteronism and disrupts functional zonation.  J Clin Invest  2020 01 02;130(1):83-93. doi:10.1172/JCI127429
  9. Masters MC, Perez J, Tassiopoulos K, Andrade A, Ellis R, Yang J, Brown TT, Palella FJ, Erlandson KM  Gait Speed Decline Is Associated with Hemoglobin A1C, Neurocognitive Impairment, and Black Race in Persons with HIV.  AIDS Res Hum Retroviruses  ;35(11-12):1065-1073. doi:10.1089/AID.2019.0101
  10. Robertson K, Landay A, Miyahara S, Vecchio A, Masters MC, Brown TT, Taiwo BO  Limited correlation between systemic biomarkers and neurocognitive performance before and during HIV treatment.  J Neurovirol  2020 02;26(1):107-113. doi:10.1007/s13365-019-00795-2
  11. Kelly SG, Masters MC, Taiwo BO  Initial Antiretroviral Therapy in an Integrase Inhibitor Era: Can We Do Better?  Infect Dis Clin North Am  2019 09;33(3):681-692. pii:S0891-5520(19)30039-X
  12. Garcia-Moreno SA, Lin YT, Futtner CR, Salamone IM, Capel B, Maatouk DM  CBX2 is required to stabilize the testis pathway by repressing Wnt signaling.  PLoS Genet  2019 05;15(5):e1007895. doi:10.1371/journal.pgen.1007895
  13. Dapas M, Sisk R, Legro RS, Urbanek M, Dunaif A, Hayes MG  Family-based quantitative trait meta-analysis implicates rare noncoding variants in DENND1A in polycystic ovary syndrome.  J Clin Endocrinol Metab  2019 Apr 30;. pii:jc.2018-02496
  14. Levine JA, Karam SL, O'Connor C, Kumar S, Soundarrajan M, McConnell D, Ammar AT, Gale AM, Zimmerman D, Szmuilowicz ED  CENTRAL DIABETES INSIPIDUS AND CHEMOTHERAPY: USE OF A CONTINUOUS ARGININE VASOPRESSIN INFUSION FOR FLUID AND SODIUM BALANCE.  AACE Clin Case Rep  ;4(6):e487-e492. doi:10.4158/ACCR-2018-0165
  15. Zelikovich AS, Quattrocelli M, Salamone IM, Kuntz NL, McNally EM  Moderate exercise improves function and increases adiponectin in the mdx mouse model of muscular dystrophy.  Sci Rep  2019 04 08;9(1):5770. doi:10.1038/s41598-019-42203-z
  16. Li S, Fong KW, Gritsina G, Zhang A, Zhao JC, Kim J, Sharp A, Yuan W, Aversa C, Yang XJ, Nelson PS, Feng FY, Chinnaiyan AM, de Bono JS, Morrissey C, Rettig MB, Yu J  Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer.  Cancer Res  2019 05 15;79(10):2580-2592. doi:10.1158/0008-5472.CAN-18-2812
  17. Garcia-Moreno SA, Futtner CR, Salamone IM, Gonen N, Lovell-Badge R, Maatouk DM  Gonadal supporting cells acquire sex-specific chromatin landscapes during mammalian sex determination.  Dev Biol  2019 02 15;446(2):168-179. pii:S0012-1606(18)30497-4
  18. Kim J, Lee Y, Lu X, Song B, Fong KW, Cao Q, Licht JD, Zhao JC, Yu J  Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator.  Cell Rep  2018 12 04;25(10):2808-2820.e4. pii:S2211-1247(18)31798-4
  19. Pusec CM, De Jesus A, Khan MW, Terry AR, Ludvik AE, Xu K, Giancola N, Pervaiz H, Daviau Smith E, Ding X, Harrison S, Chandel NS, Becker TC, Hay N, Ardehali H, Cordoba-Chacon J, Layden BT  Hepatic HKDC1 Expression Contributes to Liver Metabolism.  Endocrinology  2019 02 01;160(2):313-330. doi:10.1210/en.2018-00887
  20. Chen W, Hoffmann AD, Liu H, Liu X  Organotropism: new insights into molecular mechanisms of breast cancer metastasis.  NPJ Precis Oncol  2018;2(1):4. doi:10.1038/s41698-018-0047-0
  21. Gerber C, Cai X, Lee J, Craven T, Scialla J, Souma N, Srivastava A, Mehta R, Paluch A, Hodakowski A, Frazier R, Carnethon MR, Wolf MS, Isakova T  Incidence and Progression of Chronic Kidney Disease in Black and White Individuals with Type 2 Diabetes.  Clin J Am Soc Nephrol  2018 06 07;13(6):884-892. doi:10.2215/CJN.11871017
  22. Ramos EK, Hoffmann AD, Gerson SL, Liu H  New Opportunities and Challenges to Defeat Cancer Stem Cells.  Trends Cancer  2017 11;3(11):780-796. pii:S2405-8033(17)30174-7
  23. Eren M, Place AT, Thomas PM, Flevaris P, Miyata T, Vaughan DE  PAI-1 is a critical regulator of FGF23 homeostasis.  Sci Adv  2017 09;3(9):e1603259. doi:10.1126/sciadv.1603259
  24. Villa SR, Mishra RK, Zapater JL, Priyadarshini M, Gilchrist A, Mancebo H, Schiltz GE, Layden BT  Homology modeling of FFA2 identifies novel agonists that potentiate insulin secretion.  J Investig Med  2017 12;65(8):1116-1124. doi:10.1136/jim-2017-000523
  25. Sam S, Vellanki P, Yalamanchi SK, Bergman RN, Dunaif A  Exaggerated glucagon responses to hypoglycemia in women with polycystic ovary syndrome.  Metabolism  2017 06;71:125-131. pii:S0026-0495(17)30088-4
  26. Gorsic LK, Kosova G, Werstein B, Sisk R, Legro RS, Hayes MG, Teixeira JM, Dunaif A, Urbanek M  Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome.  J Clin Endocrinol Metab  2017 08 01;102(8):2862-2872. doi:10.1210/jc.2017-00612
  27. Kim J, Jin H, Zhao JC, Yang YA, Li Y, Yang X, Dong X, Yu J  FOXA1 inhibits prostate cancer neuroendocrine differentiation.  Oncogene  2017 07 13;36(28):4072-4080. doi:10.1038/onc.2017.50
  28. Sandler V, Reisetter AC, Bain JR, Muehlbauer MJ, Nodzenski M, Stevens RD, Ilkayeva O, Lowe LP, Metzger BE, Newgard CB, Scholtens DM, Lowe WL,   Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes.  Diabetologia  2017 03;60(3):518-530. doi:10.1007/s00125-016-4182-2
  29. Fong KW, Zhao JC, Kim J, Li S, Yang YA, Song B, Rittie L, Hu M, Yang X, Perbal B, Yu J  Polycomb-Mediated Disruption of an Androgen Receptor Feedback Loop Drives Castration-Resistant Prostate Cancer.  Cancer Res  2017 01 15;77(2):412-422. doi:10.1158/0008-5472.CAN-16-1949
  30. Ludvik AE, Pusec CM, Priyadarshini M, Angueira AR, Guo C, Lo A, Hershenhouse KS, Yang GY, Ding X, Reddy TE, Lowe WL, Layden BT  HKDC1 Is a Novel Hexokinase Involved in Whole-Body Glucose Use.  Endocrinology  2016 09;157(9):3452-61. doi:10.1210/en.2016-1288
  31. Villa SR, Priyadarshini M, Fuller MH, Bhardwaj T, Brodsky MR, Angueira AR, Mosser RE, Carboneau BA, Tersey SA, Mancebo H, Gilchrist A, Mirmira RG, Gannon M, Layden BT  Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival.  Sci Rep  2016 06 21;6:28159. doi:10.1038/srep28159
  32. Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F  Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male.  Cell Metab  2016 May 10;23(5):837-51. doi:10.1016/j.cmet.2016.03.015
  33. Dapas M, Kandpal M, Bi Y, Davuluri RV  Comparative evaluation of isoform-level gene expression estimation algorithms for RNA-seq and exon-array platforms.  Brief Bioinform  2017 03 01;18(2):260-269. doi:10.1093/bib/bbw016
  34. Monsivais D, Dyson MT, Yin P, Navarro A, Coon JS, Pavone ME, Bulun SE  Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation.  Fertil Steril  2016 05;105(5):1266-1273. pii:S0015-0282(16)00047-9