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Below is a list of publications associated with NUPEDHA.

  1. DeLacey S, Gurra M, Arzu J, Lowe LP, Lowe WL, Scholtens DM, Josefson JL  Leptin and adiposity measures from birth to later childhood: Findings from the Hyperglycemia and Adverse Pregnancy Outcomes Follow-Up Study.  Pediatr Obes  2024 Feb;19(2):e13087. doi:10.1111/ijpo.13087
  2. Leidner AS, Cai X, Zelnick LR, Lee J, Bansal N, Pasch A, Kansal M, Chen J, Anderson AH, Sondheimer JH  et al.  Fibroblast Growth Factor 23 and Risk of Heart Failure Subtype: The CRIC (Chronic Renal Insufficiency Cohort) Study.  Kidney Med  2023 Nov;5(11):100723. pii:100723
  3. Gregory S, Xu Y, Xie P, Fan J, Gao B, Mani N, Iyer R, Tang A, Wei J, Chaudhuri SM  et al.  The ubiquitin-specific peptidase 22 is a deubiquitinase of CD73 in breast cancer cells.  Am J Cancer Res  2022;12(12):5564-5575
  4. Montauti E, Weinberg SE, Chu P, Chaudhuri S, Mani NL, Iyer R, Zhou Y, Zhang Y, Liu C, Xin C  et al.  A deubiquitination module essential for Treg fitness in the tumor microenvironment.  Sci Adv  2022 Nov 25;8(47):eabo4116. pii:eabo4116
  5. Chen W, Bai Y, Kong W, Luo X, Zeng Y, Chen J, Wang X, Wu Q, Chaudhuri S, Chen J  et al.  Predictive significance of Charcot-Leyden crystal structures for nasal polyp recurrence.  Clin Transl Allergy  2022 Nov;12(11):e12212. pii:e12212
  6. Castellanos-Canales D, Fawzi AA  Global challenges in the management of diabetic retinopathy in women with pre-gestational diabetes.  Clin Exp Ophthalmol  2022 Sep;50(7):711-713. doi:10.1111/ceo.14173
  7. DeLacey S, Arzu J, Levin L, Ranganna A, Swamy A, Bianco ME  Impact of SARS-CoV2 on youth onset type 2 diabetes new diagnoses and severity.  J Diabetes  2022 Aug;14(8):532-540. doi:10.1111/1753-0407.13301
  8. Kouzu H, Tatekoshi Y, Chang HC, Shapiro JS, McGee WA, De Jesus A, Ben-Sahra I, Arany Z, Leor J, Chen C  et al.  ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice.  J Clin Invest  2022 May 16;132(10). pii:e154491
  9. Potluri T, Taylor MJ, Stulberg JJ, Lieber RL, Zhao H, Bulun SE  An estrogen-sensitive fibroblast population drives abdominal muscle fibrosis in an inguinal hernia mouse model.  JCI Insight  2022 Apr 19;7(9). pii:e152011
  10. Masters MC, Yang J, Lake JE, Abraham AG, Kingsley L, Brown TT, Palella FJ, Erlandson KM  Diabetes mellitus is associated with declines in physical function among men with and without HIV.  AIDS  2022 Apr 01;36(5):637-646. doi:10.1097/QAD.0000000000003160
  11. Salamone IM, Quattrocelli M, Barefield DY, Page PG, Tahtah I, Hadhazy M, Tomar G, McNally EM  Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms.  J Clin Invest  2022 Mar 15;132(6). pii:e149828
  12. Hsu CM, Gupta S, Tighiouart H, Goyal N, Faugno AJ, Tariq A, Raichoudhury R, Sharma JH, Meyer L, Kshirsagar RK  et al.  Kidney Recovery and Death in Critically Ill Patients With COVID-19-Associated Acute Kidney Injury Treated With Dialysis: The STOP-COVID Cohort Study.  Am J Kidney Dis  2022 Mar;79(3):404-416.e1. doi:10.1053/j.ajkd.2021.11.004
  13. Marcheva B, Weidemann BJ, Taguchi A, Perelis M, Ramsey KM, Newman MV, Kobayashi Y, Omura C, Manning Fox JE, Lin H  et al.  P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure.  Elife  2022 Feb 21;11. pii:e75132
  14. DeLacey S, Josefson JL  A Mini-Review of Pediatric Anthropometrics as Predictors of Future Insulin Resistance.  Front Endocrinol (Lausanne)  2022;13:826430. pii:826430
  15. Sato T, Shapiro JS, Chang HC, Miller RA, Ardehali H  Aging is associated with increased brain iron through cortex-derived hepcidin expression.  Elife  2022 Jan 11;11. pii:e73456
  16. Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S  et al.  HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease.  Mol Cell  2021 Dec 16;81(24):5052-5065.e6. doi:10.1016/j.molcel.2021.10.028
  17. Zhang Y, Gui M, Wang Y, Mani N, Chaudhuri S, Gao B, Li H, Kanwar YS, Lewis SA, Dumas SN  et al.  Inositol-Requiring Enzyme 1α-Mediated Synthesis of Monounsaturated Fatty Acids as a Driver of B Cell Differentiation and Lupus-like Autoimmune Disease.  Arthritis Rheumatol  2021 Dec;73(12):2314-2326. doi:10.1002/art.41883
  18. Jezmir JL, Bharadwaj M, Chaitoff A, Diephuis B, Crowley CP, Kishore SP, Goralnick E, Merriam LT, Milliken A, Rhee C  et al.  Performance of crisis standards of care guidelines in a cohort of critically ill COVID-19 patients in the United States.  Cell Rep Med  2021 Sep 21;2(9):100376. pii:100376
  19. Vasquez CR, Gupta S, Miano TA, Roche M, Hsu J, Yang W, Holena DN, Reilly JP, Schrauben SJ, Leaf DE  et al.  Identification of Distinct Clinical Subphenotypes in Critically Ill Patients With COVID-19.  Chest  2021 Sep;160(3):929-943. doi:10.1016/j.chest.2021.04.062
  20. Masters MC, Perez J, Wu K, Ellis RJ, Goodkin K, Koletar SL, Andrade A, Yang J, Brown TT, Palella FJ  et al.  Baseline Neurocognitive Impairment (NCI) Is Associated With Incident Frailty but Baseline Frailty Does Not Predict Incident NCI in Older Persons With Human Immunodeficiency Virus (HIV).  Clin Infect Dis  2021 Aug 16;73(4):680-688. doi:10.1093/cid/ciab122
  21. Churpek MM, Gupta S, Spicer AB, Parker WF, Fahrenbach J, Brenner SK, Leaf DE,   Hospital-Level Variation in Death for Critically Ill Patients with COVID-19.  Am J Respir Crit Care Med  2021 Aug 15;204(403-411):403-11. doi:10.1164/rccm.202012-4547OC
  22. Mathews KS, Soh H, Shaefi S, Wang W, Bose S, Coca S, Gupta S, Hayek SS, Srivastava A, Brenner SK  et al.  Prone Positioning and Survival in Mechanically Ventilated Patients With Coronavirus Disease 2019-Related Respiratory Failure.  Crit Care Med  2021 Jul 01;49(7):1026-1037. doi:10.1097/CCM.0000000000004938
  23. Koleini N, Shapiro JS, Geier J, Ardehali H  Ironing out mechanisms of iron homeostasis and disorders of iron deficiency.  J Clin Invest  2021 Jun 01;131(11). pii:e148671
  24. Chang HC, Shapiro JS, Jiang X, Senyei G, Sato T, Geier J, Sawicki KT, Ardehali H  Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8.  Elife  2021 Apr 09;10. pii:e65158
  25. Seki T, Yanaihara N, Shapiro JS, Saito M, Tabata J, Yokomizo R, Noguchi D, Kuroda T, Kawabata A, Suzuki J  et al.  Interleukin-6 as an enhancer of anti-angiogenic therapy for ovarian clear cell carcinoma.  Sci Rep  2021 Apr 08;11(1):7689. pii:7689
  26. Levine JA, Olivares S, Miyata T, Vaughan DE, Henkel AS  Inhibition of PAI-1 Promotes Lipolysis and Enhances Weight Loss in Obese Mice.  Obesity (Silver Spring)  2021 Apr;29(4):713-720. doi:10.1002/oby.23112
  27. Kumar RN, Masters MC, Williams J, Morrison LR, Galvin S, Krueger KM  Evaluation of Adherence to Dual-Energy X-Ray Absorptiometry Scan Ordering for Persons Living with HIV at a Tertiary Medical Center.  AIDS Patient Care STDS  2021 Feb;35(2):31-32. doi:10.1089/apc.2020.0250
  28. Soundarrajan M, Deng J, Kwasny M, Rubert NC, Nelson PC, El-Seoud DA, Landsberg L, Neff LM  Activated brown adipose tissue and its relationship to adiposity and metabolic markers: an exploratory study.  Adipocyte  2020 Dec;9(1):87-95. doi:10.1080/21623945.2020.1724740
  29. Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM  et al.  A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.  Genes Dev  2020 Aug 01;34(15-16):1089-1105. doi:10.1101/gad.338178.120
  30. Dapas M, Lin FTJ, Nadkarni GN, Sisk R, Legro RS, Urbanek M, Hayes MG, Dunaif A  Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.  PLoS Med  2020 Jun;17(6):e1003132. pii:e1003132
  31. Dapas M, Dunaif A  The contribution of rare genetic variants to the pathogenesis of polycystic ovary syndrome.  Curr Opin Endocr Metab Res  2020 Jun;12:26-32. doi:10.1016/j.coemr.2020.02.011
  32. Ghafourian K, Shapiro JS, Goodman L, Ardehali H  Iron and Heart Failure: Diagnosis, Therapies, and Future Directions.  JACC Basic Transl Sci  2020 Mar;5(3):300-313. doi:10.1016/j.jacbts.2019.08.009
  33. Pottinger TD, Puckelwartz MJ, Pesce LL, Robinson A, Kearns S, Pacheco JA, Rasmussen-Torvik LJ, Smith ME, Chisholm R, McNally EM  Pathogenic and Uncertain Genetic Variants Have Clinical Cardiac Correlates in Diverse Biobank Participants.  J Am Heart Assoc  2020 Feb 04;9(3):e013808. pii:e013808
  34. Robertson K, Landay A, Miyahara S, Vecchio A, Masters MC, Brown TT, Taiwo BO  Limited correlation between systemic biomarkers and neurocognitive performance before and during HIV treatment.  J Neurovirol  2020 Feb;26(1):107-113. doi:10.1007/s13365-019-00795-2
  35. Taylor MJ, Ullenbruch MR, Frucci EC, Rege J, Ansorge MS, Gomez-Sanchez CE, Begum S, Laufer E, Breault DT, Rainey WE  Chemogenetic activation of adrenocortical Gq signaling causes hyperaldosteronism and disrupts functional zonation.  J Clin Invest  2020 Jan 02;130(1):83-93. doi:10.1172/JCI127429
  36. Masters MC, Krueger KM, Williams JL, Morrison L, Cohn SE  Beyond one pill, once daily: current challenges of antiretroviral therapy management in the United States.  Expert Rev Clin Pharmacol  2019 Dec;12(12):1129-1143. doi:10.1080/17512433.2019.1698946
  37. Masters MC, Perez J, Tassiopoulos K, Andrade A, Ellis R, Yang J, Brown TT, Palella FJ, Erlandson KM  Gait Speed Decline Is Associated with Hemoglobin A1C, Neurocognitive Impairment, and Black Race in Persons with HIV.  AIDS Res Hum Retroviruses  2019;35(11-12):1065-1073. doi:10.1089/AID.2019.0101
  38. Kelly SG, Masters MC, Taiwo BO  Initial Antiretroviral Therapy in an Integrase Inhibitor Era: Can We Do Better?  Infect Dis Clin North Am  2019 Sep;33(3):681-692. doi:10.1016/j.idc.2019.05.003
  39. Dapas M, Sisk R, Legro RS, Urbanek M, Dunaif A, Hayes MG  Family-Based Quantitative Trait Meta-Analysis Implicates Rare Noncoding Variants in DENND1A in Polycystic Ovary Syndrome.  J Clin Endocrinol Metab  2019 Sep 01;104(9):3835-3850. doi:10.1210/jc.2018-02496
  40. Garcia-Moreno SA, Lin YT, Futtner CR, Salamone IM, Capel B, Maatouk DM  CBX2 is required to stabilize the testis pathway by repressing Wnt signaling.  PLoS Genet  2019 May;15(5):e1007895. pii:e1007895
  41. Li S, Fong KW, Gritsina G, Zhang A, Zhao JC, Kim J, Sharp A, Yuan W, Aversa C, Yang XJ  et al.  Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer.  Cancer Res  2019 May 15;79(10):2580-2592. doi:10.1158/0008-5472.CAN-18-2812
  43. Zelikovich AS, Quattrocelli M, Salamone IM, Kuntz NL, McNally EM  Moderate exercise improves function and increases adiponectin in the mdx mouse model of muscular dystrophy.  Sci Rep  2019 Apr 08;9(1):5770. pii:5770
  44. Garcia-Moreno SA, Futtner CR, Salamone IM, Gonen N, Lovell-Badge R, Maatouk DM  Gonadal supporting cells acquire sex-specific chromatin landscapes during mammalian sex determination.  Dev Biol  2019 Feb 15;446(2):168-179. doi:10.1016/j.ydbio.2018.12.023
  45. Pusec CM, De Jesus A, Khan MW, Terry AR, Ludvik AE, Xu K, Giancola N, Pervaiz H, Daviau Smith E, Ding X  et al.  Hepatic HKDC1 Expression Contributes to Liver Metabolism.  Endocrinology  2019 Feb 01;160(2):313-330. doi:10.1210/en.2018-00887