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Northwestern University Feinberg School of Medicine
Program in Endocrinology, Diabetes & Hormone Action

Publications

Below is a list of publications associated with NUPEDHA.

  1. Dieguez AC, Kuang A, Josefson JL, Scholtens DM, Lowe WL, Hayes MG, Hivert MF  In Utero Exposure to Maternal Hyperglycemia and Offspring Type 2 Diabetes Genetic Risk Score Are Independently Associated With Risk of Impaired Glucose Tolerance in Youth.  Diabetes Care  2025 Aug 01;48(8):1356-1360. doi:10.2337/dc24-2891
  2. You T, Zandigohar M, Potluri T, Piehl N, Coon V JS, Baker E, Kafali M, Dai Y, Stulberg JJ, Escobar DJ  et al.  Role of progesterone action in inguinal hernia formation via skeletal muscle fibrosis and atrophy.  JCI Insight  2025 Jul 22;10(14). pii:e193208
  3. Lopez GC, Van Camp LD, Kovaleski RF, Schaid MD, Sherathiya VN, Cox JM, Lerner TN  Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning.  Curr Biol  2025 May 19;35(10):2433-2443.e5. doi:10.1016/j.cub.2025.04.006
  4. Potluri T, You T, Yin P, Coon J, Stulberg JJ, Dai Y, Escobar DJ, Lieber RL, Zhao H, Bulun SE  Estrogen receptor-α ablation reverses muscle fibrosis and inguinal hernias.  J Clin Invest  2025 Feb 04;135(6). pii:e179137
  5. Castellanos-Canales D, Decker NL, Fukuyama H, Duffy BV, Fawzi AA  RELIABILITY OF CLINICAL GRADING OF DIABETIC RETINOPATHY COMPARED WITH GRADING OF ULTRA-WIDEFIELD IMAGES.  Retina  2024 Aug 01;44(8):1279-1287. doi:10.1097/IAE.0000000000004140
  6. Waypa GB, Smith KA, Mungai PT, Dudley VJ, Helmin KA, Singer BD, Peek CB, Bass J, Nelson L, Shah SJ  et al.  Mitochondria regulate proliferation in adult cardiac myocytes.  J Clin Invest  2024 May 09;134(13). pii:e165482
  7. Lorch CM, Hayes NW, Xia JL, Fleps SW, McMorrow HE, Province HS, Frydman JA, Parker JG, Beutler LR  Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake.  Cell Rep  2024 Feb 27;43(2):113675. doi:10.1016/j.celrep.2024.113675
  8. DeLacey S, Gurra M, Arzu J, Lowe LP, Lowe WL, Scholtens DM, Josefson JL  Leptin and adiposity measures from birth to later childhood: Findings from the Hyperglycemia and Adverse Pregnancy Outcomes Follow-Up Study.  Pediatr Obes  2024 Feb;19(2):e13087. doi:10.1111/ijpo.13087
  9. Leidner AS, Cai X, Zelnick LR, Lee J, Bansal N, Pasch A, Kansal M, Chen J, Anderson AH, Sondheimer JH  et al.  Fibroblast Growth Factor 23 and Risk of Heart Failure Subtype: The CRIC (Chronic Renal Insufficiency Cohort) Study.  Kidney Med  2023 Nov;5(11):100723. pii:100723
  10. Shapiro JS, Chang HC, Tatekoshi Y, Zhao Z, Waxali ZS, Hong BJ, Chen H, Geier JA, Bartom ET, De Jesus A  et al.  Iron drives anabolic metabolism through active histone demethylation and mTORC1.  Nat Cell Biol  2023 Oct;25(10):1478-1494. doi:10.1038/s41556-023-01225-6
  11. Decker NL, Duffy BV, Boughanem GO, Fukuyama H, Castellanos Canales D, Nesper PL, Gill MK, Fawzi AA  Macular Perfusion Deficits on OCT Angiography Correlate with Nonperfusion on Ultrawide-field Fluorescein Angiography in Diabetic Retinopathy.  Ophthalmol Retina  2023 Aug;7(8):692-702. doi:10.1016/j.oret.2023.04.003
  12. Cardona Z, Sosman JA, Chandra S, Huang W  Endocrine side effects of immune checkpoint inhibitors.  Front Endocrinol (Lausanne)  2023;14:1157805. pii:1157805
  13. Friedman JG, Cardona Matos Z, Szmuilowicz ED, Aleppo G  Use of Continuous Glucose Monitors to Manage Type 1 Diabetes Mellitus: Progress, Challenges, and Recommendations.  Pharmgenomics Pers Med  2023;16:263-276. doi:10.2147/PGPM.S374663
  14. Gregory S, Xu Y, Xie P, Fan J, Gao B, Mani N, Iyer R, Tang A, Wei J, Chaudhuri SM  et al.  The ubiquitin-specific peptidase 22 is a deubiquitinase of CD73 in breast cancer cells.  Am J Cancer Res  2022;12(12):5564-5575
  15. Montauti E, Weinberg SE, Chu P, Chaudhuri S, Mani NL, Iyer R, Zhou Y, Zhang Y, Liu C, Xin C  et al.  A deubiquitination module essential for Treg fitness in the tumor microenvironment.  Sci Adv  2022 Nov 25;8(47):eabo4116. pii:eabo4116
  16. Chen W, Bai Y, Kong W, Luo X, Zeng Y, Chen J, Wang X, Wu Q, Chaudhuri S, Chen J  et al.  Predictive significance of Charcot-Leyden crystal structures for nasal polyp recurrence.  Clin Transl Allergy  2022 Nov;12(11):e12212. pii:e12212
  17. Castellanos-Canales D, Fawzi AA  Global challenges in the management of diabetic retinopathy in women with pre-gestational diabetes.  Clin Exp Ophthalmol  2022 Sep;50(7):711-713. doi:10.1111/ceo.14173
  18. DeLacey S, Arzu J, Levin L, Ranganna A, Swamy A, Bianco ME  Impact of SARS-CoV2 on youth onset type 2 diabetes new diagnoses and severity.  J Diabetes  2022 Aug;14(8):532-540. doi:10.1111/1753-0407.13301
  19. Kouzu H, Tatekoshi Y, Chang HC, Shapiro JS, McGee WA, De Jesus A, Ben-Sahra I, Arany Z, Leor J, Chen C  et al.  ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice.  J Clin Invest  2022 May 16;132(10). pii:e154491
  20. Potluri T, Taylor MJ, Stulberg JJ, Lieber RL, Zhao H, Bulun SE  An estrogen-sensitive fibroblast population drives abdominal muscle fibrosis in an inguinal hernia mouse model.  JCI Insight  2022 Apr 19;7(9). pii:e152011
  21. Masters MC, Yang J, Lake JE, Abraham AG, Kingsley L, Brown TT, Palella FJ, Erlandson KM  Diabetes mellitus is associated with declines in physical function among men with and without HIV.  AIDS  2022 Apr 01;36(5):637-646. doi:10.1097/QAD.0000000000003160
  22. Salamone IM, Quattrocelli M, Barefield DY, Page PG, Tahtah I, Hadhazy M, Tomar G, McNally EM  Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms.  J Clin Invest  2022 Mar 15;132(6). pii:e149828
  23. Hsu CM, Gupta S, Tighiouart H, Goyal N, Faugno AJ, Tariq A, Raichoudhury R, Sharma JH, Meyer L, Kshirsagar RK  et al.  Kidney Recovery and Death in Critically Ill Patients With COVID-19-Associated Acute Kidney Injury Treated With Dialysis: The STOP-COVID Cohort Study.  Am J Kidney Dis  2022 Mar;79(3):404-416.e1. doi:10.1053/j.ajkd.2021.11.004
  24. Marcheva B, Weidemann BJ, Taguchi A, Perelis M, Ramsey KM, Newman MV, Kobayashi Y, Omura C, Manning Fox JE, Lin H  et al.  P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure.  Elife  2022 Feb 21;11. pii:e75132
  25. DeLacey S, Josefson JL  A Mini-Review of Pediatric Anthropometrics as Predictors of Future Insulin Resistance.  Front Endocrinol (Lausanne)  2022;13:826430. pii:826430
  26. Sato T, Shapiro JS, Chang HC, Miller RA, Ardehali H  Aging is associated with increased brain iron through cortex-derived hepcidin expression.  Elife  2022 Jan 11;11. pii:e73456
  27. Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S  et al.  HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease.  Mol Cell  2021 Dec 16;81(24):5052-5065.e6. doi:10.1016/j.molcel.2021.10.028
  28. Zhang Y, Gui M, Wang Y, Mani N, Chaudhuri S, Gao B, Li H, Kanwar YS, Lewis SA, Dumas SN  et al.  Inositol-Requiring Enzyme 1α-Mediated Synthesis of Monounsaturated Fatty Acids as a Driver of B Cell Differentiation and Lupus-like Autoimmune Disease.  Arthritis Rheumatol  2021 Dec;73(12):2314-2326. doi:10.1002/art.41883
  29. Jezmir JL, Bharadwaj M, Chaitoff A, Diephuis B, Crowley CP, Kishore SP, Goralnick E, Merriam LT, Milliken A, Rhee C  et al.  Performance of crisis standards of care guidelines in a cohort of critically ill COVID-19 patients in the United States.  Cell Rep Med  2021 Sep 21;2(9):100376. pii:100376
  30. Vasquez CR, Gupta S, Miano TA, Roche M, Hsu J, Yang W, Holena DN, Reilly JP, Schrauben SJ, Leaf DE  et al.  Identification of Distinct Clinical Subphenotypes in Critically Ill Patients With COVID-19.  Chest  2021 Sep;160(3):929-943. doi:10.1016/j.chest.2021.04.062
  31. Masters MC, Perez J, Wu K, Ellis RJ, Goodkin K, Koletar SL, Andrade A, Yang J, Brown TT, Palella FJ  et al.  Baseline Neurocognitive Impairment (NCI) Is Associated With Incident Frailty but Baseline Frailty Does Not Predict Incident NCI in Older Persons With Human Immunodeficiency Virus (HIV).  Clin Infect Dis  2021 Aug 16;73(4):680-688. doi:10.1093/cid/ciab122
  32. Churpek MM, Gupta S, Spicer AB, Parker WF, Fahrenbach J, Brenner SK, Leaf DE,   Hospital-Level Variation in Death for Critically Ill Patients with COVID-19.  Am J Respir Crit Care Med  2021 Aug 15;204(403-411):403-11. doi:10.1164/rccm.202012-4547OC
  33. Mathews KS, Soh H, Shaefi S, Wang W, Bose S, Coca S, Gupta S, Hayek SS, Srivastava A, Brenner SK  et al.  Prone Positioning and Survival in Mechanically Ventilated Patients With Coronavirus Disease 2019-Related Respiratory Failure.  Crit Care Med  2021 Jul 01;49(7):1026-1037. doi:10.1097/CCM.0000000000004938
  34. Koleini N, Shapiro JS, Geier J, Ardehali H  Ironing out mechanisms of iron homeostasis and disorders of iron deficiency.  J Clin Invest  2021 Jun 01;131(11). pii:e148671
  35. Chang HC, Shapiro JS, Jiang X, Senyei G, Sato T, Geier J, Sawicki KT, Ardehali H  Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8.  Elife  2021 Apr 09;10. pii:e65158
  36. Seki T, Yanaihara N, Shapiro JS, Saito M, Tabata J, Yokomizo R, Noguchi D, Kuroda T, Kawabata A, Suzuki J  et al.  Interleukin-6 as an enhancer of anti-angiogenic therapy for ovarian clear cell carcinoma.  Sci Rep  2021 Apr 08;11(1):7689. pii:7689
  37. Levine JA, Olivares S, Miyata T, Vaughan DE, Henkel AS  Inhibition of PAI-1 Promotes Lipolysis and Enhances Weight Loss in Obese Mice.  Obesity (Silver Spring)  2021 Apr;29(4):713-720. doi:10.1002/oby.23112
  38. Kumar RN, Masters MC, Williams J, Morrison LR, Galvin S, Krueger KM  Evaluation of Adherence to Dual-Energy X-Ray Absorptiometry Scan Ordering for Persons Living with HIV at a Tertiary Medical Center.  AIDS Patient Care STDS  2021 Feb;35(2):31-32. doi:10.1089/apc.2020.0250
  39. Soundarrajan M, Deng J, Kwasny M, Rubert NC, Nelson PC, El-Seoud DA, Landsberg L, Neff LM  Activated brown adipose tissue and its relationship to adiposity and metabolic markers: an exploratory study.  Adipocyte  2020 Dec;9(1):87-95. doi:10.1080/21623945.2020.1724740
  40. Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM  et al.  A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.  Genes Dev  2020 Aug 01;34(15-16):1089-1105. doi:10.1101/gad.338178.120
  41. Dapas M, Lin FTJ, Nadkarni GN, Sisk R, Legro RS, Urbanek M, Hayes MG, Dunaif A  Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.  PLoS Med  2020 Jun;17(6):e1003132. pii:e1003132
  42. Dapas M, Dunaif A  The contribution of rare genetic variants to the pathogenesis of polycystic ovary syndrome.  Curr Opin Endocr Metab Res  2020 Jun;12:26-32. doi:10.1016/j.coemr.2020.02.011
  43. Ghafourian K, Shapiro JS, Goodman L, Ardehali H  Iron and Heart Failure: Diagnosis, Therapies, and Future Directions.  JACC Basic Transl Sci  2020 Mar;5(3):300-313. doi:10.1016/j.jacbts.2019.08.009
  44. Pottinger TD, Puckelwartz MJ, Pesce LL, Robinson A, Kearns S, Pacheco JA, Rasmussen-Torvik LJ, Smith ME, Chisholm R, McNally EM  Pathogenic and Uncertain Genetic Variants Have Clinical Cardiac Correlates in Diverse Biobank Participants.  J Am Heart Assoc  2020 Feb 04;9(3):e013808. pii:e013808
  45. Robertson K, Landay A, Miyahara S, Vecchio A, Masters MC, Brown TT, Taiwo BO  Limited correlation between systemic biomarkers and neurocognitive performance before and during HIV treatment.  J Neurovirol  2020 Feb;26(1):107-113. doi:10.1007/s13365-019-00795-2
  46. Taylor MJ, Ullenbruch MR, Frucci EC, Rege J, Ansorge MS, Gomez-Sanchez CE, Begum S, Laufer E, Breault DT, Rainey WE  Chemogenetic activation of adrenocortical Gq signaling causes hyperaldosteronism and disrupts functional zonation.  J Clin Invest  2020 Jan 02;130(1):83-93. doi:10.1172/JCI127429